Query author contributions in Reactome
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Details on Person C-Jun NH2 terminal kinases are stress activated MAPKs, also ...
| Class:Id | Summation:446240 |
|---|---|
| _displayName | C-Jun NH2 terminal kinases are stress activated MAPKs, also ... |
| _timestamp | 2010-10-15 20:37:26 |
| created | [InstanceEdit:446232] Shamovsky, V, 2009-11-11 |
| modified | [InstanceEdit:977266] D'Eustachio, P, 2010-10-15 |
| text | C-Jun NH2 terminal kinases are stress activated MAPKs, also known as SAPKs. The JNK pathway is activated by heat shock, or inflammatory cytokines, or UV radiation. The JNKs are encoded by at least three genes: JNK1/SAPK-gamma, JNK2/SAPK-alpha and JNK3/ SAPK-beta. Activation of JNKs is mediated by activated TAK1 which phosphorylates two dual specificity enzymes MKK4 (MAPK kinase 4) and MKK7(MAPK kinase 7). |
| (summation) | [Pathway:437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation [Gallus gallus] |
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No pathways have been reviewed or authored by C-Jun NH2 terminal kinases are stress activated MAPKs, also ... (446240)
