Query author contributions in Reactome
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Details on Person The interleukin 1 receptor antagonist protein (ILRAP or IL1R...
| Class:Id | Summation:445759 |
|---|---|
| _displayName | The interleukin 1 receptor antagonist protein (ILRAP or IL1R... |
| _timestamp | 2010-05-17 16:59:13 |
| created | [InstanceEdit:445754] Jupe, S, 2009-11-05 |
| modified | [InstanceEdit:446142] Jupe, S, 2009-11-09 [InstanceEdit:507731] Jupe, S, 2010-02-08 [InstanceEdit:561121] Jupe, S, 2010-03-25 [InstanceEdit:744685] Jupe, S, 2010-05-17 |
| text | The interleukin 1 receptor antagonist protein (ILRAP or IL1RN) is a member of the IL1 family that binds to IL1R1 (and with much lower affinity IL1R2) but does not elicit a signaling response. By competing with IL1 for IL1R1 binding ILRAP acts as a natural antagonist, inhibiting the biological actions of both agonist forms of IL1 (IL1 alpha and IL1 beta). |
| (summation) | [Reaction:445757] IL1 receptor antagonist protein binds Interleukin 1 receptors [Homo sapiens] |
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No pathways have been reviewed or authored by The interleukin 1 receptor antagonist protein (ILRAP or IL1R... (445759)
