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Details on Person UniProt:P16255 SRP14
| Class:Id | ReferenceGeneProduct:445171 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-110 added on Sat February 7 2015;initiator methionine:1 for 445171 removed on Fri Nov 03 2023;initiator methionine: for 445171 added on Fri Nov 03 2023;initiator methionine: for 445171 removed on Fri Aug 15 2025;initiator methionine:1 for 445171 added on Fri Aug 15 2025 |
| _displayName | UniProt:P16255 SRP14 |
| _timestamp | 2025-08-15 22:12:09 |
| chain | initiator methionine:1 chain:2-110 |
| checksum | 0D01DF1392082FD9 |
| comment | FUNCTION Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:6938958). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:6413076, PubMed:6938958). The complex of SRP9 and SRP14 is required for SRP RNA binding (PubMed:6413076, PubMed:6938958).SUBUNIT Heterodimer with SRP9; binds RNA as heterodimer (PubMed:6413076). Component of a signal recognition particle complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9 (PubMed:6413076, PubMed:6938958).SUBCELLULAR LOCATION Belongs to the SRP14 family. |
| created | [InstanceEdit:445185] May, B, 2009-10-29 |
| description | recommendedName: Signal recognition particle 14 kDa protein shortName: SRP14 |
| geneName | SRP14 |
| identifier | P16255 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Signal recognition particle |
| modified | [InstanceEdit:445291] May, B, 2009-10-29 [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8856987] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9773244] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | SRP14 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | SRP14_CANLF Q28277 |
| sequenceLength | 110 |
| species | [Species:49646] Canis familiaris |
| (referenceEntity) | [EntityWithAccessionedSequence:445191] SRP14_CANFA [cytosol] [Canis familiaris] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:P16255 SRP14 (445171)
