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Details on Person Urotensin-II (U2) is a vasoactive 'somatostatin-like' cyclic...
| Class:Id | Summation:445106 |
|---|---|
| _displayName | Urotensin-II (U2) is a vasoactive 'somatostatin-like' cyclic... |
| _timestamp | 2009-10-27 17:16:20 |
| created | [InstanceEdit:445098] Jupe, S, 2009-10-27 |
| literatureReference | [LiteratureReference:445112] Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14 [LiteratureReference:445104] Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain |
| text | Urotensin-II (U2) is a vasoactive 'somatostatin-like' cyclic peptide originally isolated from fish spinal cords. It was found to activate GPR14 later renamed Urotensin II receptor (U2R).
U2 is the most potent known vasoconstrictor. A second ligand for U2R, urotensin-related peptide or Urotensin 2B, was identified as an extract from rat brains, and shown to activate rat and human U2R. |
| (summation) | [Reaction:445113] Urotensin-2 receptor binds urotensin-2 and 2B [Homo sapiens] |
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No pathways have been reviewed or authored by Urotensin-II (U2) is a vasoactive 'somatostatin-like' cyclic... (445106)
