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Details on Person Phosphorylation of L1 by ERK

Class:IdReaction:445079
_displayNamePhosphorylation of L1 by ERK
_doReleaseTRUE
_timestamp2010-12-02 14:38:28
authored[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
catalystActivity[CatalystActivity:111895] MAP kinase activity of p-T185,Y187-MAPK1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:445090] Garapati, P V, 2009-10-27
edited[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
input[SimpleEntity:113592] ATP [cytosol]
[EntityWithAccessionedSequence:109853] p-T185,Y187-MAPK1 [cytosol] [Homo sapiens]
[Complex:392746] L1:AP-2 Clathrin complex [endosome] [Homo sapiens]
literatureReference[LiteratureReference:444908] Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization
[LiteratureReference:445034] A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis
modified[InstanceEdit:446625] Garapati, P V, 2009-11-16
[InstanceEdit:447049] Garapati, P V, 2009-11-19
[InstanceEdit:447051] Garapati, P V, 2009-11-19
[InstanceEdit:448355] Garapati, P V, 2009-11-24
[InstanceEdit:513003] Garapati, P V, 2010-02-16
[InstanceEdit:532606] Garapati, P V, 2010-03-01
[InstanceEdit:549059] Garapati, P V, 2010-03-16
[InstanceEdit:750980] Garapati, P V, 2010-05-19
[InstanceEdit:772533] Garapati, P V, 2010-05-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylation of L1 by ERK
output[SimpleEntity:29370] ADP [cytosol]
[Complex:445005] pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] [Homo sapiens]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:513001] Maness, PF, 2010-02-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105250] R-HSA-445079.2
summation[Summation:444937] L1 cross linking can activate MAPK cascade components MEK1/2...
(hasEvent)[Pathway:437239] Recycling pathway of L1 [Homo sapiens]
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