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Details on Person Activation of Rac1 by VAV2

Class:IdReaction:445064
_displayNameActivation of Rac1 by VAV2
_doReleaseTRUE
_timestamp2010-12-02 14:41:04
authored[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
catalystActivity[CatalystActivity:442283] guanyl-nucleotide exchange factor activity of p-Y172-VAV2 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:445090] Garapati, P V, 2009-10-27
edited[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
input[SimpleEntity:29438] GTP [cytosol]
[Complex:445010] RAC1:GDP [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:444930] Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling
[LiteratureReference:445034] A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis
modified[InstanceEdit:445145] Garapati, P V, 2009-10-27
[InstanceEdit:446625] Garapati, P V, 2009-11-16
[InstanceEdit:447049] Garapati, P V, 2009-11-19
[InstanceEdit:447051] Garapati, P V, 2009-11-19
[InstanceEdit:448355] Garapati, P V, 2009-11-24
[InstanceEdit:513003] Garapati, P V, 2010-02-16
[InstanceEdit:532606] Garapati, P V, 2010-03-01
[InstanceEdit:750980] Garapati, P V, 2010-05-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivation of Rac1 by VAV2
output[SimpleEntity:29420] GDP [cytosol]
[Complex:442641] RAC1:GTP [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:513001] Maness, PF, 2010-02-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105760] R-HSA-445064.2
summation[Summation:444946] The small GTPase p21Rac1 is one of the important targets of ...
(hasEvent)[Pathway:445144] Signal transduction by L1 [Homo sapiens]
(precedingEvent)[Reaction:445072] Interaction of PAK1 with Rac1-GTP [Homo sapiens]
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No pathways have been reviewed or authored by Activation of Rac1 by VAV2 (445064)