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Query author contributions in Reactome

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Details on Person L1 crosslinking leads to the tyrosine phosphorylation and ac...

Class:IdSummation:444945
_displayNameL1 crosslinking leads to the tyrosine phosphorylation and ac...
_timestamp2009-12-30 21:52:31
created[InstanceEdit:444932] Garapati, P V, 2009-10-27
literatureReference[LiteratureReference:444930] Adhesion molecule L1 stimulates neuronal migration through Vav2-Pak1 signaling
modified[InstanceEdit:446621] Garapati, P V, 2009-11-16
[InstanceEdit:451256] Garapati, P V, 2009-12-30
textL1 crosslinking leads to the tyrosine phosphorylation and activation of VAV2. Tyr-172 in VAV2 binds to the DBL homology region autoinhibiting its GEF-activity. Tyrosine kinase src may phosphorylate this residue and relieve the autoinhibition.
(summation)[BlackBoxEvent:445085] Phosphorylation of VAV2 [Homo sapiens]
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