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Details on Person Relaxin receptor 2 (RXFP2 or LGR8) is activated by porcine r...
| Class:Id | Summation:444886 |
|---|---|
| _displayName | Relaxin receptor 2 (RXFP2 or LGR8) is activated by porcine r... |
| _timestamp | 2009-10-27 11:57:41 |
| created | [InstanceEdit:444871] Jupe, S, 2009-10-27 |
| literatureReference | [LiteratureReference:444882] H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2 [LiteratureReference:444899] INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent [LiteratureReference:375241] Relaxin family peptide receptors--former orphans reunite with their parent ligands to activate multiple signalling pathways |
| text | Relaxin receptor 2 (RXFP2 or LGR8) is activated by porcine relaxin, human relaxin-2 and insulin-like peptide-3 (INSL3). Relaxin affinity is lower than for Relaxin receptor 1, suggesting that this receptor functions as an INSL3 receptor. |
| (summation) | [Reaction:444879] Relaxin receptor 2 binds relaxin 2 and INSL3 [Homo sapiens] |
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No pathways have been reviewed or authored by Relaxin receptor 2 (RXFP2 or LGR8) is activated by porcine r... (444886)
