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Details on Person Relaxin receptor 2 binds relaxin 2 and INSL3

Class:Id	Reaction:444879
_displayName	Relaxin receptor 2 binds relaxin 2 and INSL3
_doRelease	TRUE
_timestamp	2010-12-02 14:37:45
authored	[InstanceEdit:444770] Jupe, S, 2009-10-26
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:444871] Jupe, S, 2009-10-27
edited	[InstanceEdit:532507] Jupe, S, 2010-03-01
input	[EntityWithAccessionedSequence:444844] RXFP2 [plasma membrane] [Homo sapiens] [DefinedSet:444902] RXFP2 ligands [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:444882] H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
modified	[InstanceEdit:514599] Jupe, S, 2010-02-17 [InstanceEdit:532503] Jupe, S, 2010-03-01 [InstanceEdit:532504] Jupe, S, 2010-03-01 [InstanceEdit:532571] Jupe, S, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Relaxin receptor 2 binds relaxin 2 and INSL3
output	[Complex:444892] RXFP2:RXFP2 ligands [plasma membrane] [Homo sapiens]
releaseDate	2010-03-16
reviewed	[InstanceEdit:450112] D'Eustachio, P, 2009-12-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105103] R-HSA-444879.2
summation	[Summation:444886] Relaxin receptor 2 (RXFP2 or LGR8) is activated by porcine r...
(hasEvent)	[Pathway:444821] Relaxin receptors [Homo sapiens]
(precedingEvent)	[Reaction:744887] Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs [Homo sapiens] [Reaction:9660828] ADORA2B:Ade-Rib binds heterometric G-protein Gs [Homo sapiens]
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No pathways have been reviewed or authored by Relaxin receptor 2 binds relaxin 2 and INSL3 (444879)