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Details on Person Relaxin 3 receptor 2 binds relaxin 3 and INSL5

Class:Id	Reaction:444859
_displayName	Relaxin 3 receptor 2 binds relaxin 3 and INSL5
_doRelease	TRUE
_timestamp	2010-12-02 14:32:12
authored	[InstanceEdit:444852] Jupe, S, 2009-10-26
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:444871] Jupe, S, 2009-10-27
edited	[InstanceEdit:532507] Jupe, S, 2010-03-01
input	[EntityWithAccessionedSequence:444826] RXFP4 [plasma membrane] [Homo sapiens] [DefinedSet:444889] RXFP4 ligands [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:444869] Identification of relaxin-3/INSL7 as a ligand for GPCR142 [LiteratureReference:444875] INSL5 is a high affinity specific agonist for GPCR142 (GPR100)
modified	[InstanceEdit:514599] Jupe, S, 2010-02-17 [InstanceEdit:532503] Jupe, S, 2010-03-01 [InstanceEdit:532504] Jupe, S, 2010-03-01 [InstanceEdit:532571] Jupe, S, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Relaxin 3 receptor 2 binds relaxin 3 and INSL5
output	[Complex:444907] RXFP4:RXFP4 ligands [plasma membrane] [Homo sapiens]
releaseDate	2010-03-16
reviewed	[InstanceEdit:450112] D'Eustachio, P, 2009-12-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104105] R-HSA-444859.2
summation	[Summation:444876] Relaxin-3 receptor 2 (RXFP4 or GPR100) is activated by relax...
(hasEvent)	[Pathway:444821] Relaxin receptors [Homo sapiens]
(precedingEvent)	[Reaction:749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi [Homo sapiens]
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No pathways have been reviewed or authored by Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (444859)