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Details on Person Zn2+ is a potent and effective agonist of GPR39, signaling e...
| Class:Id | Summation:444576 |
|---|---|
| _displayName | Zn2+ is a potent and effective agonist of GPR39, signaling e... |
| _timestamp | 2017-10-06 15:47:30 |
| created | [InstanceEdit:444580] Jupe, S, 2009-10-23 |
| literatureReference | [LiteratureReference:444578] Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39 [LiteratureReference:9024688] Common structural basis for constitutive activity of the ghrelin receptor family [LiteratureReference:9024686] GPR39 signaling is stimulated by zinc ions but not by obestatin [LiteratureReference:9024690] Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake |
| modified | [InstanceEdit:9024695] Jupe, Steve, 2017-10-06 |
| text | Zn2+ is a potent and effective agonist of GPR39, signaling effectively through the Gq pathway (Holst et al. 2004, 2007) and Gs (Zhang et al. 2005, Holst et al. 2007). |
| (summation) | [Reaction:444572] Zinc is an agonist of GPR39 [Homo sapiens] |
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No pathways have been reviewed or authored by Zn2+ is a potent and effective agonist of GPR39, signaling e... (444576)
