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Details on Person Cho transports from the extracellular space to the cytosol

Class:Id	Reaction:444433
_displayName	Cho transports from the extracellular space to the cytosol
_doRelease	TRUE
_timestamp	2025-08-18 09:05:46
authored	[InstanceEdit:444460] Jassal, Bijay, 2009-10-23
catalystActivity	[CatalystActivity:444463] choline transmembrane transporter activity of CTL1-5 [plasma membrane]
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:444460] Jassal, Bijay, 2009-10-23
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
input	[SimpleEntity:264638] Cho [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:444435] Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells [LiteratureReference:444455] Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss [LiteratureReference:372536] Functional characterization of the human high-affinity choline transporter [LiteratureReference:1483013] Molecular characterization of the family of choline transporter-like proteins and their splice variants [LiteratureReference:1482871] An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins
modified	[InstanceEdit:446288] Jassal, Bijay, 2009-11-12 [InstanceEdit:1602443] Williams, MG, 2011-09-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963933] Stephan, Ralf, 2025-08-18
name	Cho transports from the extracellular space to the cytosol CTL1-5 can mediate the uptake of choline
output	[SimpleEntity:264618] Cho [cytosol]
precedingEvent	[Reaction:372519] AcCho is hydrolyzed to Cho and acetate by ACHE [Homo sapiens]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105868] R-HSA-444433.3
summation	[Summation:444441] Choline (Cho) transports from the extracellular space throug...
(hasEvent)	[Pathway:1483191] Synthesis of PC [Homo sapiens] [Pathway:5619103] Defective SLC44A4 causes sialidosis [Homo sapiens] [Pathway:9958517] SLC-mediated bile acid transport [Homo sapiens]
(precedingEvent)	[Reaction:264622] Cho is acetylated to AcCho by CHAT [Homo sapiens] [Reaction:1483004] Cho is phosphorylated to PCho by CHK dimer [Homo sapiens] [Reaction:1483019] Cho is acetylated to AcCho by CHAT [Homo sapiens] [Reaction:6797956] SLC44A1 and SLC44A2 transport Cho from cytosol to mitochondrial matrix [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788561] Update Tracker - [Reaction:444433] Cho transports from the extracellular space to the cytosol - v41:[modifyText] [_UpdateTracker:9789028] Update Tracker - [Reaction:444433] Cho transports from the extracellular space to the cytosol - v39:[addLiteratureReference, modifyText]
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