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Details on Person The MAPK level components of this cascade are p38MAPK-alpha,...

Class:IdSummation:444066
_displayNameThe MAPK level components of this cascade are p38MAPK-alpha,...
_timestamp2010-10-15 20:36:35
created[InstanceEdit:444069] Shamovsky, V, 2009-10-20
modified[InstanceEdit:977264] D'Eustachio, P, 2010-10-15
textThe MAPK level components of this cascade are p38MAPK-alpha, -beta, -gamma and -sigma. All of those isoforms are activated by phosphorylation of the Thr and Tyr in the Thr-Gly-Tyr motif in their activation loops.
(summation)[Reaction:438019] activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 [Gallus gallus]
[Reaction:450333] Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 [Homo sapiens]
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