Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person GAT1-3 mediate Na+/Cl- dependent GABA transport

Class:Id	Reaction:444007
_displayName	GAT1-3 mediate Na+/Cl- dependent GABA transport
_doRelease	TRUE
_timestamp	2025-06-14 15:02:42
authored	[InstanceEdit:444041] Jassal, Bijay, 2009-10-20
catalystActivity	[CatalystActivity:444014] gamma-aminobutyric acid:sodium:chloride symporter activity of SLC6A GABA transporters [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:444041] Jassal, Bijay, 2009-10-20
crossReference	[DatabaseIdentifier:9956804] RHEA:70688
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
input	[SimpleEntity:352003] GABA [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:188972] Cl- [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:444034] Cloning of the human brain GABA transporter [LiteratureReference:444023] Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2 [LiteratureReference:444013] Cloning of the human homologue of the GABA transporter GAT-3 and identification of a novel inhibitor with selectivity for this site [LiteratureReference:444016] Role of Cl- in electrogenic Na+-coupled cotransporters GAT1 and SGLT1
modified	[InstanceEdit:446288] Jassal, Bijay, 2009-11-12 [InstanceEdit:918019] Mahajan, SS, 2010-07-30 [InstanceEdit:918271] Mahajan, SS, 2010-08-03 [InstanceEdit:936523] Mahajan, SS, 2010-08-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9956811] Stephan, Ralf, 2025-06-14
name	GAT1-3 mediate Na+/Cl- dependent GABA transport
output	[SimpleEntity:352011] GABA [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:352022] Cl- [cytosol]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:918281] Mahajan, SS, 2010-08-03
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104973] R-HSA-444007.3
summation	[Summation:444003] Four transporters mediate GABA uptake in the brain, GAT1-3 a...
(hasEvent)	[Pathway:442660] SLC-mediated transport of neurotransmitters [Homo sapiens] [Pathway:888593] Reuptake of GABA [Homo sapiens]
(precedingEvent)	[Reaction:428625] Vesicular inhibitory amino acid transport [Homo sapiens] [Reaction:888592] Loading of GABA into clathrin sculpted GABA transport vesicle lumen [Homo sapiens] [BlackBoxEvent:9653180] GABA translocates from cytosol to mitochondrial matrix [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by GAT1-3 mediate Na+/Cl- dependent GABA transport (444007)