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Details on Person Atypical chemokine receptor 2 (ACKR2, CCBP2, D6) is a promis...
| Class:Id | Summation:443958 |
|---|---|
| _displayName | Atypical chemokine receptor 2 (ACKR2, CCBP2, D6) is a promis... |
| _timestamp | 2019-08-15 14:51:20 |
| created | [InstanceEdit:443969] Jupe, S, 2009-10-20 |
| literatureReference | [LiteratureReference:443983] Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6 [LiteratureReference:8957202] Regulation of the immune and inflammatory responses by the 'atypical' chemokine receptor D6 |
| modified | [InstanceEdit:8957203] Jupe, Steve, 2017-01-24 [InstanceEdit:9658504] Jassal, Bijay, 2019-08-15 |
| text | Atypical chemokine receptor 2 (ACKR2, CCBP2, D6) is a promiscuous chemokine receptor which has no known signalling function and is therefore considered to be a 'silent' or 'scavenger' receptor. ACKR2 negatively regulates inflammatory responses by binding CC chemokines, targeting them for degradation following receptor internalization (Fra et al. 2003, Bonecchi et al. 2004, Graham & Locati 2013). |
| (summation) | [Reaction:443986] Receptor ACKR2 binds most inflammatory CC chemokines [Homo sapiens] |
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No pathways have been reviewed or authored by Atypical chemokine receptor 2 (ACKR2, CCBP2, D6) is a promis... (443958)
