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Details on Person SHC1 dissociates from integrin alphaIIb beta3

Class:Id	BlackBoxEvent:443910
_displayName	SHC1 dissociates from integrin alphaIIb beta3
_doRelease	TRUE
_timestamp	2010-12-02 14:42:03
authored	[InstanceEdit:435013] Akkerman, JW, 2009-09-04
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:443903] Jupe, S, 2009-10-16
edited	[InstanceEdit:939817] Jupe, S, 2010-09-01
input	[Complex:443900] Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:432100] Identification of shc as the primary protein binding to the tyrosine-phosphorylated beta 3 subunit of alpha IIbbeta 3 during outside-in integrin platelet signaling [LiteratureReference:188605] Not all Shc's roads lead to Ras
modified	[InstanceEdit:443911] Jupe, S, 2009-10-16 [InstanceEdit:686124] Jupe, S, 2010-05-06 [InstanceEdit:727831] Jupe, S, 2010-05-12 [InstanceEdit:939908] Jupe, S, 2010-09-02 [InstanceEdit:939917] Jupe, S, 2010-09-02 [InstanceEdit:940430] Jupe, S, 2010-09-03 [InstanceEdit:941884] Jupe, S, 2010-09-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SHC1 dissociates from integrin alphaIIb beta3
output	[Complex:354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:74684] p-Y427-SHC1 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:443905] SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow [Homo sapiens] [Reaction:432096] Activated integrin alphaIIb beta3 binds SHC1 [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:939806] Heemskerk, JW, 2010-09-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105957] R-HSA-443910.2
summation	[Summation:443901] In a mechanism that is presumed to be analagous to signaling...
(hasEvent)	[Pathway:354192] Integrin signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790259] Update Tracker - [BlackBoxEvent:443910] SHC1 dissociates from integrin alphaIIb beta3 - v34:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by SHC1 dissociates from integrin alphaIIb beta3 (443910)