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Details on Person TXA2 is hydrolysed to TXB2

Class:Id	Reaction:443894
_displayName	TXA2 is hydrolysed to TXB2
_doRelease	TRUE
_timestamp	2016-11-10 00:57:07
authored	[InstanceEdit:2142839] Williams, MG, 2012-02-24
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:443892] Jupe, S, 2009-10-14
edited	[InstanceEdit:2142839] Williams, MG, 2012-02-24
input	[SimpleEntity:32879] TXA2 [endoplasmic reticulum lumen] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:443891] Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides [LiteratureReference:2161070] Substrate binding is the rate-limiting step in thromboxane synthase catalysis
modified	[InstanceEdit:443898] Jupe, S, 2009-10-14 [InstanceEdit:2161071] Williams, MG, 2012-03-07 [InstanceEdit:2162189] Williams, MG, 2012-03-15 [InstanceEdit:2201176] Williams, MG, 2012-04-17 [InstanceEdit:2240987] D'Eustachio, P, 2012-05-08 [InstanceEdit:2569041] D'Eustachio, P, 2012-11-10 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TXA2 is hydrolysed to TXB2 Thromboxane A2 degenerates to thromboxane B2
output	[SimpleEntity:443890] TXB2 [endoplasmic reticulum lumen]
precedingEvent	[Reaction:76500] TBXAS1 isomerises PGH2 to TXA2 [Homo sapiens] [Reaction:140359] PGG2 is reduced to PGH2 by PTGS1 [Homo sapiens] [Reaction:2309773] PGG2 is reduced to PGH2 by PTGS2 [Homo sapiens]
releaseDate	2009-09-30
reviewed	[InstanceEdit:2569042] Rush, MG, 2012-11-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200472] R-HSA-443894.3
summation	[Summation:443893] Thromboxane A2 (TXA2) contains an unstable ether linkage tha...
(hasEvent)	[Pathway:2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) [Homo sapiens]
(precedingEvent)	[Reaction:2161732] TXB2 is converted to 11dh-TXB2 by TXDH [Homo sapiens]
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No pathways have been reviewed or authored by TXA2 is hydrolysed to TXB2 (443894)