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Details on Person DM GRASP/ALCAM/BEN is one of the heterodimerizing partners ...

Class:IdSummation:443559
_displayNameDM GRASP/ALCAM/BEN is one of the heterodimerizing partners ...
_timestamp2010-03-16 17:38:30
created[InstanceEdit:443547] Garapati, P V, 2009-10-09
literatureReference[LiteratureReference:443556] Heterophilic interactions of DM-GRASP: GRASP-NgCAM interactions involved in neurite extension
[LiteratureReference:549026] ALCAM regulates mediolateral retinotopic mapping in the superior colliculus
modified[InstanceEdit:451256] Garapati, P V, 2009-12-30
[InstanceEdit:549028] Garapati, P V, 2010-03-16
textDM GRASP/ALCAM/BEN is one of the heterodimerizing partners for L1/NgCAM. Interation between L1/NgCAM and DM GRASP in the growth cone membrane is involved in L1 stimulated neurite outgrowth. Trans binding of L1 on retinal growth cones to ALCAM on the superior colliculus potentiates adhesion, leading to correct synaptic targeting.
(summation)[Reaction:443780] Cis-heterodimerization of L1 and DM-GRASP/ALCAM/BEN [Homo sapiens]
[Reaction:443781] Cis-heterodimerization of NgCAM and DM-GRASP/ALCAM [Gallus gallus]
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