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Details on Person Jupe, S, 2009-10-05

Class:Id	InstanceEdit:443386
_displayName	Jupe, S, 2009-10-05
_timestamp	2009-10-05 12:44:20
author	[Person:391309] Jupe, Steve
dateTime	2009-10-05 16:43:49
(created)	[Reaction:443383] PKC alpha phosphorylates AKT1 at S473 [Rattus norvegicus] [EntityWithAccessionedSequence:443384] p-Akt1 (T308) [plasma membrane] [Rattus norvegicus] [CatalystActivity:443385] protein serine/threonine kinase activity of Protein kinase C, alpha type [cytosol] [Summation:443387] Two conventional PKC isoforms, PKC alpha and PKC betaII hav... [Complex:443388] p-Akt1(T308, S473):PDK1 [plasma membrane] [Rattus norvegicus] [EntityWithAccessionedSequence:443389] p-Akt1 (T308, S473) [plasma membrane] [Rattus norvegicus] [Reaction:443390] PKCalpha/betaII phosphorylate AKT at S473 [Homo sapiens] [Complex:443391] p-Akt1(T308):PDK1 [plasma membrane] [Rattus norvegicus]
(modified)	[Pathway:198203] PI3K/AKT activation [Homo sapiens] [Reaction:198298] AKT translocates to the nucleus [Homo sapiens] [Pathway:198323] AKT phosphorylates targets in the cytosol [Homo sapiens] [Summation:198351] In line with activation of PI3-kinase (PI3K) by other recept... [Summation:198363] Once AKT is localized at the plasma membrane, it is phosphor... [Summation:202572] AKT1 (PKB alpha) consists of an N-terminal PH domain, a kina... [Reaction:202692] PIP3 binds to RhoA and activates it [Homo sapiens] [Complex:443028] PDK1:AKT [cytosol] [Homo sapiens] [Reaction:443034] PDK1 and AKT associate in the cytoplasm [Homo sapiens]
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No pathways have been reviewed or authored by Jupe, S, 2009-10-05 (443386)