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Details on Person PKC alpha phosphorylates AKT1 at S473

Class:Id	Reaction:443383
_displayName	PKC alpha phosphorylates AKT1 at S473
_timestamp	2016-12-01 00:31:52
catalystActivity	[CatalystActivity:443385] protein serine/threonine kinase activity of Protein kinase C, alpha type [cytosol]
compartment	[Compartment:947587] cytoplasmic side of plasma membrane
created	[InstanceEdit:443386] Jupe, S, 2009-10-05
input	[Complex:443391] p-Akt1(T308):PDK1 [plasma membrane] [Rattus norvegicus]
isChimeric	FALSE
literatureReference	[LiteratureReference:162393] Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase Calpha in endothelial cells
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8949915] D'Eustachio, Peter, 2016-12-01
name	PKC alpha phosphorylates AKT1 at S473
output	[Complex:443388] p-Akt1(T308, S473):PDK1 [plasma membrane] [Rattus norvegicus]
species	[Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:8909534] R-RNO-443383.1
summation	[Summation:443387] Two conventional PKC isoforms, PKC alpha and PKC betaII hav...
(inferredFrom)	[Reaction:443390] PKCalpha/betaII phosphorylate AKT at S473 [Homo sapiens]
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No pathways have been reviewed or authored by PKC alpha phosphorylates AKT1 at S473 (443383)