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Details on Person Activated FGFR dimer complex phosphorylates STUMPS

Class:Id	Reaction:443192
_displayName	Activated FGFR dimer complex phosphorylates STUMPS
_doRelease	FALSE
_timestamp	2017-06-27 17:34:29
authored	[InstanceEdit:443152] Williams, MG, 2009-10-02
catalystActivity	[CatalystActivity:443246] protein tyrosine kinase activity of Phospho FGFR [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:443210] Williams, MG, 2009-10-02
figure	[Figure:443339] /figures/DrosFGFRA05.jpg
input	[Complex:443111] FGF:Phospho FGFR:STUMPS dimer complex [plasma membrane] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:443350] Downstream-of-FGFR is a fibroblast growth factor-specific scaffolding protein and recruits Corkscrew upon receptor activation [LiteratureReference:443232] A functional domain of Dof that is required for fibroblast growth factor signaling
modified	[InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	Activated FGFR dimer complex phosphorylates STUMPS
output	[Complex:443128] FGF:Phospho FGFR:Phospho STUMPS dimer complex [plasma membrane] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:443260] FGFR dimer complex autphosphorylates and is activated [Drosophila melanogaster] [Reaction:443257] FGF ligands bind to FGFR dimer extracellular domains [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8882765] R-DME-443192.1
summation	[Summation:443365] The adaptor protein STUMPS is phosphorylated at Tyr515 by th...
(hasEvent)	[Pathway:443263] Assembly of the FGFR complex [Drosophila melanogaster]
(precedingEvent)	[Reaction:443097] VAP binds to phosphorylated FGFR [Drosophila melanogaster] [Reaction:443311] CSW binds to phosphorylated STUMPS [Drosophila melanogaster]
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No pathways have been reviewed or authored by Activated FGFR dimer complex phosphorylates STUMPS (443192)