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Details on Person Nuclear export of p38 MAPK mediated by its substrate MAPKAPK2 or 3

Class:Id	Reaction:442862
_displayName	Nuclear export of p38 MAPK mediated by its substrate MAPKAPK2 or 3
_doRelease	TRUE
_timestamp	2010-12-02 14:38:47
authored	[InstanceEdit:438031] Shamovsky, V, 2009-09-22
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:442879] Shamovsky, V, 2009-09-29
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[Reaction:450257] Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 [Homo sapiens]
input	[Complex:442915] phospho -p38 MAPK : phospho- MAPKAPK 2 or phospho MAPKAPK3 [nucleoplasm] [Gallus gallus]
literatureReference	[LiteratureReference:442922] Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2 [LiteratureReference:442896] Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export
modified	[InstanceEdit:446254] Shamovsky, V, 2009-11-11 [InstanceEdit:451546] Shamovsky, V, 2010-01-05 [InstanceEdit:451974] Shamovsky, V, 2010-01-14 [InstanceEdit:571363] Shamovsky, V, 2010-04-09 [InstanceEdit:674730] Shamovsky, V, 2010-05-05 [InstanceEdit:680255] Shamovsky, V, 2010-05-05 [InstanceEdit:749438] Shamovsky, V, 2010-05-18 [InstanceEdit:796983] Shamovsky, V, 2010-05-24 [InstanceEdit:844695] Shamovsky, V, 2010-05-28 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Nuclear export of p38 MAPK mediated by its substrate MAPKAPK2 or 3
output	[Complex:442925] phospho -p38 MAPK : phospho- MAPKAPK 2 or phospho-MAPKAPK3 [cytosol] [Gallus gallus]
precedingEvent	[Reaction:442913] Active p38 MAPK phosphorylates MAPKAPK2 or 3 [Gallus gallus] [Reaction:438019] activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 [Gallus gallus]
releaseDate	2010-12-14
reviewed	[InstanceEdit:789693] D'Eustachio, P, 2010-05-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1105325] R-GGA-442862.2
summation	[Summation:444071] p38 MAPK alpha does not have a nuclear export signal (NES) a...
(hasEvent)	[Pathway:437980] Activated TAK1 mediates p38 MAP kinase phosphorylation [Gallus gallus]
(updatedInstance)	[_UpdateTracker:9788320] Update Tracker - [Reaction:442862] Nuclear export of p38 MAPK mediated by its substrate MAPKAPK2 or 3 - v43:[modifyText]
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