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Details on Person Pparg:Rxra heterodimer binds to PPARG corepressors

Class:Id	Reaction:442515
_displayName	Pparg:Rxra heterodimer binds to PPARG corepressors
_doRelease	TRUE
_timestamp	2014-02-03 19:03:39
authored	[InstanceEdit:420937] May, B, 2009-05-15 01:16:49
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:442522] May, B, 2009-09-27
edited	[InstanceEdit:381396] May, B, Gopinathrao, G, 2008-11-19 19:22:37 [InstanceEdit:420937] May, B, 2009-05-15 01:16:49
input	[Complex:442510] Pparg:Rxra Heterodimer [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:442520] Hdac3 [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:442459] Ncor1 [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:442511] Ncor2 [nucleoplasm] [Mus musculus]
literatureReference	[LiteratureReference:381274] Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha [LiteratureReference:381307] Down-regulation of histone deacetylases stimulates adipocyte differentiation [LiteratureReference:381333] The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor gamma transcriptional activity and repress 3T3-L1 adipogenesis [LiteratureReference:381273] Dual DNA-binding specificity of peroxisome-proliferator-activated receptor gamma controlled by heterodimer formation with retinoid X receptor alpha [LiteratureReference:381326] Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element [LiteratureReference:381354] Transcriptional control of adipocyte formation
modified	[InstanceEdit:381391] May, B, 2008-11-19 19:19:43 [InstanceEdit:381397] May, B, 2008-11-19 19:24:45 [InstanceEdit:383210] Gopinathrao, G, 2008-11-24 14:43:07 [InstanceEdit:386982] Gopinathrao, G, 2008-11-29 01:56:59 [InstanceEdit:420924] May, B, 2009-05-15 01:13:07 [InstanceEdit:422150] D'Eustachio, P, 2009-05-26 22:09:50 [InstanceEdit:425289] May, B, 2009-06-03 [InstanceEdit:425871] May, B, 2009-06-08 [InstanceEdit:425941] Matthews, L, 2009-06-09 [InstanceEdit:434253] May, B, 2009-08-27 [InstanceEdit:435266] May, B, 2009-09-09 [InstanceEdit:442525] May, B, 2009-09-27 [InstanceEdit:556759] May, B, 2010-03-23 [InstanceEdit:766126] May, B, 2010-05-21 [InstanceEdit:847703] May, B, 2010-05-30 [InstanceEdit:976245] May, B, 2010-10-12 [InstanceEdit:977273] May, B, 2010-10-18 [InstanceEdit:1008273] May, B, 2010-11-11 [InstanceEdit:1082224] May, B, 2010-11-29 [InstanceEdit:1183014] May, B, 2011-02-09 [InstanceEdit:2876561] May, B, 2012-12-23 [InstanceEdit:5251386] May, B, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Pparg:Rxra heterodimer binds to PPARG corepressors
output	[Complex:442484] Pparg:Rxra:Corepressor Complex [nucleoplasm] [Mus musculus]
precedingEvent	[BlackBoxEvent:442475] Expression of Pparg [Mus musculus] [BlackBoxEvent:442516] Expression of Cebpb [Mus musculus] [BlackBoxEvent:442509] Expression of Klf5 [Mus musculus] [BlackBoxEvent:977286] Expression of Ebf1 [Mus musculus] [BlackBoxEvent:977389] Expression of Cebpd [Mus musculus]
releaseDate	2011-03-15
reviewed	[InstanceEdit:1183001] Sethi, JK, 2011-02-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1225007] R-MMU-442515.2
summation	[Summation:442523] In mouse 3T3-L1 cells, the PPARG:RXRA heterodimer binds spec...
(inferredFrom)	[Reaction:381290] PPARG:RXRA heterodimer binds to PPARG corepressors [Homo sapiens]
(precedingEvent)	[Reaction:556760] Pparg:Rxra heterodimer binds to fatty acids [Mus musculus]
(replacementInstances)	[_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032443] Deletion of instance: 442533
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No pathways have been reviewed or authored by Pparg:Rxra heterodimer binds to PPARG corepressors (442515)