Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person HELZ2 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:442499
_displayNameHELZ2 [nucleoplasm]
_timestamp2025-10-03 22:03:15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:442522] May, B, 2009-09-27
endCoordinate2846
modified[InstanceEdit:442525] May, B, 2009-09-27
[InstanceEdit:3448660] Wu, G, 2013-05-16
[InstanceEdit:3632907] Wu, G, 2013-05-28
[InstanceEdit:9967565] D'Eustachio, Peter, 2025-10-03
nameHELZ2
PRIC285
Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein
PR285_HUMAN
referenceEntity[ReferenceGeneProduct:413536] UniProt:Q9BYK8 HELZ2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1225197] R-HSA-442499.2
startCoordinate1
(hasComponent)[Complex:381367] PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] [Homo sapiens]
(hasMember)[DefinedSet:400216] Coactivators of PPARalpha [nucleoplasm] [Homo sapiens]
[DefinedSet:8962899] Proteins overexpressed after IL27 stimulation [cytosol] [Homo sapiens]
(inferredFrom)[EntityWithAccessionedSequence:5334183] mPDIP1 [nucleoplasm] [Mus musculus]
(input)[Reaction:381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands [Homo sapiens]
(updatedInstance)[_UpdateTracker:9886725] Update Tracker - [EntityWithAccessionedSequence:442499] HELZ2 [nucleoplasm] - v45:[addName]
[_UpdateTracker:9972826] Update Tracker - [EntityWithAccessionedSequence:442499] HELZ2 [nucleoplasm] - v95:[modifyEndCoordinate]
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No pathways have been reviewed or authored by HELZ2 [nucleoplasm] (442499)