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Details on Person Expression of Cebpa

Class:Id	BlackBoxEvent:442497
_displayName	Expression of Cebpa
_doRelease	TRUE
_timestamp	2017-04-07 07:43:22
authored	[InstanceEdit:420937] May, B, 2009-05-15 01:16:49
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:442522] May, B, 2009-09-27
edited	[InstanceEdit:381396] May, B, Gopinathrao, G, 2008-11-19 19:22:37 [InstanceEdit:420937] May, B, 2009-05-15 01:16:49
input	[EntityWithAccessionedSequence:8984473] Cebpa gene [nucleoplasm] [Mus musculus]
literatureReference	[LiteratureReference:977281] Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells [LiteratureReference:977282] Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins [LiteratureReference:381236] Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade [LiteratureReference:381354] Transcriptional control of adipocyte formation
modified	[InstanceEdit:381391] May, B, 2008-11-19 19:19:43 [InstanceEdit:381397] May, B, 2008-11-19 19:24:45 [InstanceEdit:383210] Gopinathrao, G, 2008-11-24 14:43:07 [InstanceEdit:390506] May, B, 2009-02-09 20:38:31 [InstanceEdit:420925] May, B, 2009-05-15 01:13:33 [InstanceEdit:422150] D'Eustachio, P, 2009-05-26 22:09:50 [InstanceEdit:425283] May, B, 2009-06-03 [InstanceEdit:425866] May, B, 2009-06-08 [InstanceEdit:425941] Matthews, L, 2009-06-09 [InstanceEdit:434247] May, B, 2009-08-27 [InstanceEdit:435260] May, B, 2009-09-09 [InstanceEdit:442525] May, B, 2009-09-27 [InstanceEdit:556759] May, B, 2010-03-23 [InstanceEdit:766126] May, B, 2010-05-21 [InstanceEdit:847703] May, B, 2010-05-30 [InstanceEdit:976245] May, B, 2010-10-12 [InstanceEdit:977273] May, B, 2010-10-18 [InstanceEdit:1008273] May, B, 2010-11-11 [InstanceEdit:1082224] May, B, 2010-11-29 [InstanceEdit:1183014] May, B, 2011-02-09 [InstanceEdit:2026094] May, B, 2011-12-22 [InstanceEdit:2876561] May, B, 2012-12-23 [InstanceEdit:8984498] May, Bruce, 2017-04-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of Cebpa
output	[EntityWithAccessionedSequence:442502] Cebpa [nucleoplasm] [Mus musculus]
precedingEvent	[Reaction:556760] Pparg:Rxra heterodimer binds to fatty acids [Mus musculus] [Reaction:442515] Pparg:Rxra heterodimer binds to PPARG corepressors [Mus musculus] [BlackBoxEvent:977286] Expression of Ebf1 [Mus musculus] [BlackBoxEvent:442516] Expression of Cebpb [Mus musculus] [BlackBoxEvent:977389] Expression of Cebpd [Mus musculus]
regulatedBy	[PositiveRegulation:442527] Positive regulation by 'Ebf1 [nucleoplasm]' [NegativeRegulation:976216] Negative regulation by 'Tgfb1 [extracellular region]' [NegativeRegulation:976236] Negative regulation by 'Tnf [extracellular region]' [NegativeRegulation:976241] Negative regulation by 'Wnt-1 or Wnt-10b [extracellular region]'
regulationReference	[RegulationReference:9641410] Negative regulation by 'Tgfb1 [extracellular region]' Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis [RegulationReference:9641552] Negative regulation by 'Tnf [extracellular region]' TNF-alpha inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPbeta and delta [RegulationReference:9642669] Negative regulation by 'Wnt-1 or Wnt-10b [extracellular region]' Inhibition of adipogenesis by Wnt signaling [RegulationReference:9642840] Positive regulation by 'Ebf1 [nucleoplasm]' Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade
releaseDate	2011-03-15
reviewed	[InstanceEdit:1183001] Sethi, JK, 2011-02-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1224998] R-MMU-442497.5
summation	[Summation:442513] In mouse 3T3-L1 pre-adipocytes, Cebpa is expressed during ad...
(inferredFrom)	[BlackBoxEvent:560491] Expression of CEBPA [Homo sapiens]
(replacementInstances)	[_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032443] Deletion of instance: 442533
(updatedInstance)	[_UpdateTracker:9781256] Update Tracker - [BlackBoxEvent:442497] Expression of Cebpa - v61:[addInput]
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No pathways have been reviewed or authored by Expression of Cebpa (442497)