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Details on Person NCOA1 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:442496
_displayName NCOA1 [nucleoplasm]
_timestamp 2025-10-02 22:24:05
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:442522] May, B, 2009-09-27
endCoordinate 1441
modified [InstanceEdit:442525] May, B, 2009-09-27 [InstanceEdit:3448660] Wu, G, 2013-05-16 [InstanceEdit:9860202] Orlic-Milacic, Marija, 2024-01-31 [InstanceEdit:9967563] D'Eustachio, Peter, 2025-10-02
name NCOA1 Nuclear receptor coactivator 1 NCOA1_HUMAN SRC-1 Steroid receptor coactivator 1
referenceEntity [ReferenceGeneProduct:405889] UniProt:Q15788 NCOA1 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1225323] R-HSA-442496.3
startCoordinate 2
(hasCandidate) [CandidateSet:9023843] NCOAs [nucleoplasm] [Homo sapiens] [CandidateSet:9844662] Brown,beige adipocyte-specific coactivators of PPARG:RXRA [nucleoplasm] [Homo sapiens] [CandidateSet:9970995] (NCOA1, NCOA2, NCOA3) [nucleoplasm] [Homo sapiens]
(hasComponent) [Complex:381367] PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] [Homo sapiens] [Complex:5340274] NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] [Homo sapiens] [Complex:9023832] ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] [Homo sapiens] [Complex:9029599] NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] [Homo sapiens] [Complex:9035268] UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] [Homo sapiens] [Complex:9035367] SCNN1A gene:NR3C2:NR3C2 ligand:UBE2I:NCOA1 [nucleoplasm] [Homo sapiens] [Complex:9639660] SCNN1A gene:NR3C2:NR3C2 ligand:UBE2I:NCOA1:NFYC [nucleoplasm] [Homo sapiens]
(hasMember) [DefinedSet:381297] Coactivators of PPARG Target Genes [nucleoplasm] [Homo sapiens] [DefinedSet:400216] Coactivators of PPARalpha [nucleoplasm] [Homo sapiens] [DefinedSet:5340269] NCOA1,2 [nucleoplasm] [Homo sapiens] [DefinedSet:9023864] NCOA1,NCOA3 [nucleoplasm] [Homo sapiens] [DefinedSet:9851482] NCOAs (PPARG,RXRA) [nucleoplasm] [Homo sapiens] [DefinedSet:9957259] NCOA1,NCOA2,RXRA [nucleoplasm] [Homo sapiens]
(input) [Reaction:381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands [Homo sapiens] [Reaction:4085296] SUMOylation of NCOA1 with SUMO1 [Homo sapiens] [Reaction:9008270] NCOA1 binds ESR1:estrogen:TGFA gene [Homo sapiens] [Reaction:9029551] NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex [Homo sapiens] [Reaction:9029580] NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex [Homo sapiens] [Reaction:9035365] UBE2I, NCOA1 bind NR3C2:NR3C2 ligand:SCNN1A gene [Homo sapiens]
(updatedInstance) [_UpdateTracker:9972461] Update Tracker - [EntityWithAccessionedSequence:442496] NCOA1 [nucleoplasm] - v95:[modifyStartCoordinate]
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Pathways
No pathways have been reviewed or authored by NCOA1 [nucleoplasm] (442496)