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Details on Person Expression of Pparg

Class:Id	BlackBoxEvent:442475
_displayName	Expression of Pparg
_doRelease	TRUE
_timestamp	2017-04-07 07:44:50
authored	[InstanceEdit:420937] May, B, 2009-05-15 01:16:49
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:442522] May, B, 2009-09-27
edited	[InstanceEdit:381396] May, B, Gopinathrao, G, 2008-11-19 19:22:37 [InstanceEdit:420937] May, B, 2009-05-15 01:16:49
input	[EntityWithAccessionedSequence:8984484] Pparg gene [nucleoplasm] [Mus musculus]
literatureReference	[LiteratureReference:381260] Kr�ppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation [LiteratureReference:977275] Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids [LiteratureReference:442505] A role for C/EBPbeta in regulating peroxisome proliferator-activated receptor gamma activity during adipogenesis in 3T3-L1 preadipocytes [LiteratureReference:977283] Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesis [LiteratureReference:977282] Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins [LiteratureReference:381354] Transcriptional control of adipocyte formation [LiteratureReference:381298] The transcription factor CCAAT/enhancer-binding protein alpha is required for the intracellular retention of GLUT4
modified	[InstanceEdit:381391] May, B, 2008-11-19 19:19:43 [InstanceEdit:381397] May, B, 2008-11-19 19:24:45 [InstanceEdit:383210] Gopinathrao, G, 2008-11-24 14:43:07 [InstanceEdit:390506] May, B, 2009-02-09 20:38:31 [InstanceEdit:390521] May, B, 2009-02-09 20:47:43 [InstanceEdit:420937] May, B, 2009-05-15 01:16:49 [InstanceEdit:422150] D'Eustachio, P, 2009-05-26 22:09:50 [InstanceEdit:425290] May, B, 2009-06-03 [InstanceEdit:425872] May, B, 2009-06-08 [InstanceEdit:425941] Matthews, L, 2009-06-09 [InstanceEdit:434255] May, B, 2009-08-27 [InstanceEdit:435268] May, B, 2009-09-09 [InstanceEdit:435331] May, B, 2009-09-09 [InstanceEdit:442525] May, B, 2009-09-27 [InstanceEdit:556759] May, B, 2010-03-23 [InstanceEdit:766126] May, B, 2010-05-21 [InstanceEdit:847703] May, B, 2010-05-30 [InstanceEdit:976245] May, B, 2010-10-12 [InstanceEdit:977273] May, B, 2010-10-18 [InstanceEdit:977391] May, B, 2010-10-19 [InstanceEdit:1008273] May, B, 2010-11-11 [InstanceEdit:1014259] May, B, 2010-11-15 [InstanceEdit:1082224] May, B, 2010-11-29 [InstanceEdit:1183014] May, B, 2011-02-09 [InstanceEdit:2026094] May, B, 2011-12-22 [InstanceEdit:2876561] May, B, 2012-12-23 [InstanceEdit:8863173] May, Bruce, 2016-03-05 [InstanceEdit:8984498] May, Bruce, 2017-04-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of Pparg
output	[DefinedSet:442503] Pparg [nucleoplasm] [Mus musculus]
precedingEvent	[BlackBoxEvent:442516] Expression of Cebpb [Mus musculus] [BlackBoxEvent:442509] Expression of Klf5 [Mus musculus] [BlackBoxEvent:442516] Expression of Cebpb [Mus musculus] [BlackBoxEvent:977389] Expression of Cebpd [Mus musculus] [BlackBoxEvent:977286] Expression of Ebf1 [Mus musculus] [BlackBoxEvent:442516] Expression of Cebpb [Mus musculus] [BlackBoxEvent:977389] Expression of Cebpd [Mus musculus] [BlackBoxEvent:977389] Expression of Cebpd [Mus musculus]
regulatedBy	[PositiveRegulation:442524] Positive regulation by 'Cebpd [nucleoplasm]' [PositiveRegulation:442530] Positive regulation by 'Cebpa [nucleoplasm]' [PositiveRegulation:442531] Positive regulation by 'Ebf1 [nucleoplasm]' [PositiveRegulation:442532] Positive regulation by 'Cebpb [nucleoplasm]' [PositiveRegulation:442535] Positive regulation by 'Klf5 [nucleoplasm]' [NegativeRegulation:976199] Negative regulation by 'Wnt-1 or Wnt-10b [extracellular region]' [NegativeRegulation:976212] Negative regulation by 'Tnf [extracellular region]' [NegativeRegulation:976226] Negative regulation by 'Tgfb1 [extracellular region]' [PositiveGeneExpressionRegulation:8939436] Positive gene expression regulation by 'Znf638 [nucleoplasm]' [PositiveGeneExpressionRegulation:8940342] Positive gene expression regulation by 'Znf467 [nucleoplasm]'
regulationReference	[RegulationReference:9641563] Positive gene expression regulation by 'Znf467 [nucleoplasm]' Zinc finger protein 467 is a novel regulator of osteoblast and adipocyte commitment [RegulationReference:9641569] Positive regulation by 'Cebpb [nucleoplasm]' Sequential gene promoter interactions of C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis [RegulationReference:9641623] Positive gene expression regulation by 'Znf638 [nucleoplasm]' Regulation of adipocyte differentiation by the zinc finger protein ZNF638 [RegulationReference:9641664] Negative regulation by 'Tgfb1 [extracellular region]' Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis [RegulationReference:9641961] Negative regulation by 'Tnf [extracellular region]' TNF-alpha inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPbeta and delta [RegulationReference:9642199] Negative regulation by 'Wnt-1 or Wnt-10b [extracellular region]' Inhibition of adipogenesis by Wnt signaling [RegulationReference:9642212] Positive regulation by 'Ebf1 [nucleoplasm]' Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade [RegulationReference:9642585] Positive regulation by 'Cebpd [nucleoplasm]' Modulation of the murine peroxisome proliferator-activated receptor gamma 2 promoter activity by CCAAT/enhancer-binding proteins [RegulationReference:9642977] Positive regulation by 'Cebpa [nucleoplasm]' Sequential gene promoter interactions of C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis [RegulationReference:9642981] Positive regulation by 'Klf5 [nucleoplasm]' Kr�ppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation
releaseDate	2011-03-15
reviewed	[InstanceEdit:1183001] Sethi, JK, 2011-02-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:1224918] R-MMU-442475.6
summation	[Summation:442476] In mouse 3T3-L1 cells, the transcription factors Cebpb, Cebp...
(inferredFrom)	[BlackBoxEvent:381283] Expression of PPARG [Homo sapiens]
(precedingEvent)	[Reaction:442515] Pparg:Rxra heterodimer binds to PPARG corepressors [Mus musculus]
(replacementInstances)	[_Deleted:8863181] Deletion of instance: 442504 [_Deleted:9032440] Deletion of instance: 5334727 [_Deleted:9032443] Deletion of instance: 442533
(updatedInstance)	[_UpdateTracker:9774908] Update Tracker - [BlackBoxEvent:442475] Expression of Pparg - v80:[modifyText] [_UpdateTracker:9781304] Update Tracker - [BlackBoxEvent:442475] Expression of Pparg - v61:[addInput] [_UpdateTracker:9782385] Update Tracker - [BlackBoxEvent:442475] Expression of Pparg - v59:[addRegulator] [_UpdateTracker:9783119] Update Tracker - [BlackBoxEvent:442475] Expression of Pparg - v57:[addLiteratureReference, addRegulator, modifyText]
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No pathways have been reviewed or authored by Expression of Pparg (442475)