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Details on Person HDAC3 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:442464
_displayName	HDAC3 [nucleoplasm]
_timestamp	2011-06-29 20:18:19
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:442522] May, B, 2009-09-27
endCoordinate	428
modified	[InstanceEdit:442525] May, B, 2009-09-27 [InstanceEdit:1368132] May, B, 2011-06-29 [InstanceEdit:3448660] Wu, G, 2013-05-16
name	HDAC3 Histone deacetylase 3 HDAC3_HUMAN
referenceEntity	[ReferenceGeneProduct:401336] UniProt:O15379 HDAC3 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1225518] R-HSA-442464.1
startCoordinate	1
(activeUnit)	[NegativeRegulation:9008166] Negative regulation by 'RUNX2:ZNF521:HDAC3 [nucleoplasm]' [NegativeGeneExpressionRegulation:9029646] Negative gene expression regulation by 'ABCA1gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 [nucleoplasm]'
(hasComponent)	[Complex:381226] PPARG:RXRA:Corepressor Complex [nucleoplasm] [Homo sapiens] [Complex:1368079] NR1D1 (REV-ERBA):heme:Corepressor [nucleoplasm] [Homo sapiens] [Complex:4663830] HDAC3-containing complex [nucleoplasm] [Homo sapiens] [Complex:5617465] RARA,G:RXRA at HOXA1 bivalent chromatin [nucleoplasm] [Homo sapiens] [Complex:9005550] NCOR1 complex [nucleoplasm] [Homo sapiens] [Complex:9005701] NCOR2 complex [nucleoplasm] [Homo sapiens] [Complex:9008155] RUNX2:ZNF521:HDAC3 [nucleoplasm] [Homo sapiens] [Complex:9024373] NCOR:GPS2:TBL1:HDAC3 [nucleoplasm] [Homo sapiens] [Complex:9035341] SGK1:NR3C2:NR3C2 ligand:HDAC4:HDAC3 [nucleoplasm] [Homo sapiens] [Complex:9035350] TSC22D3 gene:NR3C2:NR3C2 ligand:HDAC4:HDAC3 [nucleoplasm] [Homo sapiens]
(hasMember)	[DefinedSet:205005] Histone deacetylase [nucleoplasm] [Homo sapiens] [CandidateSet:350066] HDAC [nucleoplasm] [Homo sapiens] [DefinedSet:381259] Corepressors of PPARG Target Genes [nucleoplasm] [Homo sapiens] [DefinedSet:400207] Corepressors of PPARalpha [nucleoplasm] [Homo sapiens] [DefinedSet:6808476] HDAC3,5,7 [nucleoplasm] [Homo sapiens]
(input)	[Reaction:381290] PPARG:RXRA heterodimer binds to PPARG corepressors [Homo sapiens] [Reaction:1368069] NR1D1 (REV-ERBA) binds heme, the BMAL1 (ARNTL) gene, and recruits corepressors [Homo sapiens] [Reaction:5663245] NR1D1 (REV-ERBA) binds heme, the NPAS2 gene, and recruits corepressors [Homo sapiens] [Reaction:5663252] NR1D1 (REV-ERBA) binds heme, the ELOVL3 gene, and recruits corepressors [Homo sapiens] [Reaction:5663258] NR1D1 (REV-ERBA) binds heme, the PPARGC1A gene, and recruits corepressors [Homo sapiens] [Reaction:5663265] NR1D1 (REV-ERBA) binds heme, the NR1D1 gene, and recruits corepressors [Homo sapiens] [Reaction:5663271] NR1D1 (REV-ERBA) binds heme, the CLOCK gene, and recruits corepressors [Homo sapiens] [Reaction:9008137] RUNX2 binds ZNF521 and HDAC3 [Homo sapiens] [Reaction:9035357] HDAC3,HDAC4 bind SGK1 gene:NR3C2:NR3C2 ligand [Homo sapiens] [Reaction:9035358] HDAC3,HDAC4 bind TSC22D3 gene:NR3C2:NR3C2 ligand [Homo sapiens]
(output)	[Reaction:381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands [Homo sapiens] [BlackBoxEvent:5617431] Retinoic acid activates HOXA1 chromatin [Homo sapiens]
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No pathways have been reviewed or authored by HDAC3 [nucleoplasm] (442464)