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Details on Person hZIP10 mediates zinc influx into cells

Class:Id	Reaction:442345
_displayName	hZIP10 mediates zinc influx into cells
_doRelease	TRUE
_timestamp	2025-08-13 17:47:16
authored	[InstanceEdit:442374] Jassal, Bijay, 2009-09-25
catalystActivity	[CatalystActivity:442407] zinc ion transmembrane transporter activity of SLC39A10 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:442374] Jassal, Bijay, 2009-09-25
crossReference	[DatabaseIdentifier:9958440] RHEA:29353
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
inferredFrom	[Reaction:442359] rZip10 mediates zinc influx into cells [Rattus norvegicus]
input	[SimpleEntity:158417] Zn2+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:442391] Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells [LiteratureReference:442341] Molecular cloning and functional characterization of novel zinc transporter rZip10 (Slc39a10) involved in zinc uptake across rat renal brush-border membrane
modified	[InstanceEdit:446288] Jassal, Bijay, 2009-11-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9958441] Stephan, Ralf, 2025-06-20 [InstanceEdit:9963151] Stephan, Ralf, 2025-08-13
name	hZIP10 mediates zinc influx into cells
negativePrecedingEvent	[NegativePrecedingEvent:9963153] Futile Cycle: ZnT1 mediates the efflux of zinc from the cell
output	[SimpleEntity:29426] Zn2+ [cytosol]
releaseDate	2009-12-15
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105408] R-HSA-442345.3
summation	[Summation:442337] The human gene SLC39A10 encodes the zinc transporter hZIP10....
(hasEvent)	[Pathway:442380] Zinc influx into cells by the SLC39 gene family [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963155] Futile Cycle: hZIP10 mediates zinc influx into cells [Reaction:435171] NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages [Homo sapiens] [Reaction:435375] ZnT2 facilitates zinc vesicular sequestration [Homo sapiens] [Reaction:437084] ZnT3 transports zinc into synaptic vesicles [Homo sapiens] [Reaction:437085] ZnT5 transports zinc into secretory granules in pancreatic beta cells [Homo sapiens] [Reaction:437136] SLC30A8 transports Zn2+ from cytosol to secretory granule [Homo sapiens] [Reaction:437139] ZnT8 transports zinc into the Golgi apparatus [Homo sapiens] [Reaction:9820566] ZnT5 transports zinc into the golgi apparatus [Homo sapiens]
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No pathways have been reviewed or authored by hZIP10 mediates zinc influx into cells (442345)