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Details on Person Phosphorylated tyrosine Y1175 of VEGFR2 provides the binding...

Class:IdSummation:4420173
_displayNamePhosphorylated tyrosine Y1175 of VEGFR2 provides the binding...
_timestamp2014-01-15 10:20:58
created[InstanceEdit:4420157] Garapati, P V, 2013-08-30
literatureReference[LiteratureReference:4420111] The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells
modified[InstanceEdit:5218600] Garapati, P V, 2013-12-19
[InstanceEdit:5228988] Garapati, P V, 2014-01-15
textPhosphorylated tyrosine Y1175 of VEGFR2 provides the binding site for the adaptor protein SHC-transforming protein 2 (SHC2) also referred as Shc-like protein (SCK). SCK is plausibly involved in coupling VEGFR2 to ERK (Warner et al. 2000, Ratcliffe et al. 2002).
(summation)[Reaction:4420107] p-6Y-VEGFR2 binds SHC-transforming protein 2 [Homo sapiens]
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