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Details on Person SRC1-1 binds SH2D2A and is recruited to VEGFR2

Class:Id	Reaction:4420140
_displayName	SRC1-1 binds SH2D2A and is recruited to VEGFR2
_doRelease	TRUE
_timestamp	2017-10-23 12:24:38
authored	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
edited	[InstanceEdit:4420157] Garapati, P V, 2013-08-30
input	[EntityWithAccessionedSequence:354153] SRC-1 [cytosol] [Homo sapiens] [Complex:4420137] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4420207] VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd
modified	[InstanceEdit:5218857] Garapati, P V, 2013-12-19 [InstanceEdit:5228340] Jupe, S, 2014-01-10 [InstanceEdit:5228988] Garapati, P V, 2014-01-15 [InstanceEdit:5357631] Garapati, P V, 2014-03-25 [InstanceEdit:5357638] Garapati, P V, 2014-03-25 [InstanceEdit:5432676] Garapati, P V, 2014-05-12 [InstanceEdit:5490368] Garapati, P V, 2014-05-19 [InstanceEdit:9026715] Rothfels, Karen, 2017-10-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SRC1-1 binds SH2D2A and is recruited to VEGFR2
output	[Complex:4420169] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A:SRC-1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:4420143] p-6Y-VEGFR2 binds SH2D2A [Homo sapiens] [Reaction:4420117] VEGFR2 autophosphorylates [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5432673] Welsh, Michael, Berger, Philipp, Ballmer-Hofer, Kurt, 2014-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644560] R-HSA-4420140.3
summation	[Summation:4420087] SH2D2A (also known as TSAD) bound to VEGFR2 forms a complex ...
(hasEvent)	[Pathway:4420097] VEGFA-VEGFR2 Pathway [Homo sapiens]
(precedingEvent)	[Reaction:4420206] Phosphorylation of SRC-1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780240] Update Tracker - [Reaction:4420140] SRC1-1 binds SH2D2A and is recruited to VEGFR2 - v63:[modifyText]
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