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Details on Person SH2D2A (also known as TSAD) bound to VEGFR2 forms a complex ...

Class:IdSummation:4420087
_displayNameSH2D2A (also known as TSAD) bound to VEGFR2 forms a complex ...
_timestamp2017-10-23 12:28:06
created[InstanceEdit:4420157] Garapati, P V, 2013-08-30
literatureReference[LiteratureReference:4420132] VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis
modified[InstanceEdit:5218600] Garapati, P V, 2013-12-19
[InstanceEdit:5357631] Garapati, P V, 2014-03-25
[InstanceEdit:5357638] Garapati, P V, 2014-03-25
[InstanceEdit:9026732] Rothfels, Karen, 2017-10-23
textSH2D2A (also known as TSAD) bound to VEGFR2 forms a complex with Src to regulate stress fiber formation and endothelial cell (EC) migration. This contributes to EC migration during pathological angiogenesis and thus the recruitment of SH2D2A is associated with cancer angiogenesis (Matsumoto et al. 2005).
(summation)[Reaction:4420140] SRC1-1 binds SH2D2A and is recruited to VEGFR2 [Homo sapiens]
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