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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person CFH W1183L [extracellular region]

Class:IdEntityWithAccessionedSequence:4416704
_displayNameCFH W1183L [extracellular region]
_timestamp2016-07-15 23:50:03
compartment[Compartment:984] extracellular region
created[InstanceEdit:4416674] Shamovsky, V, 2013-08-26
endCoordinate1231
hasModifiedResidue[ReplacedResidue:4416710] L-tryptophan 1183 replaced with L-leucine
literatureReference[LiteratureReference:4416712] Functional analysis in serum from atypical Hemolytic Uremic Syndrome patients reveals impaired protection of host cells associated with mutations in factor H
[LiteratureReference:4416670] Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions
[LiteratureReference:4416644] Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
nameCFH W1183L
Complement factor H W1183L variant
CFAH_HUMAN
referenceEntity[ReferenceGeneProduct:51922] UniProt:P08603 CFH [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8910685] R-HSA-4416704.1
startCoordinate19
(hasCandidate)[CandidateSet:4416627] aHUS-associated CFH variants set 2 [extracellular region] [Homo sapiens]
(hasMember)[CandidateSet:5260236] aHUS-associated CFH variants set 1 [extracellular region] [Homo sapiens]
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No pathways have been reviewed or authored by CFH W1183L [extracellular region] (4416704)
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