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Details on Person mNOTCH1 coactivator complex bind promoters of Hey genes

Class:Id	Reaction:4396387
_displayName	mNOTCH1 coactivator complex bind promoters of Hey genes
_doRelease	TRUE
_timestamp	2026-03-17 14:11:09
authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4396385] Orlic-Milacic, M, 2013-08-22
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
input	[DefinedSet:4396366] Hey Genes [nucleoplasm] [Mus musculus] [Complex:2065439] Notch1 Coactivator Complex [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2065301] Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes [LiteratureReference:9985244] Dynamic binding of RBPJ is determined by Notch signaling status
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9985246] May, Bruce, 2026-03-17
name	mNOTCH1 coactivator complex bind promoters of Hey genes
output	[Complex:4396386] mNOTCH1 Coactivator Complex:Hey Genes [nucleoplasm] [Mus musculus]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:4545346] R-MMU-4396387.3
summation	[Summation:4396381] Promoters of Hey1, Hey and Heyl genes contain conserved RBPJ...
(inferredFrom)	[Reaction:4396382] NOTCH1 Coactivator Complex binds promoters of HEY genes [Homo sapiens] [Reaction:9979248] NOTCH1 Coactivator Complex binds the HEY1 gene [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:2065441] mNOTCH1 coactivator complex positively regulates transcription of Hey1, Hey2 and Heyl [Mus musculus]
(updatedInstance)	[_UpdateTracker:9984695] Update Tracker - [Reaction:4396387] mNOTCH1 coactivator complex bind promoters of Hey genes - v96:[modifyText] [_UpdateTracker:9989651] Update Tracker - [Reaction:4396387] mNOTCH1 coactivator complex bind promoters of Hey genes - v97:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by mNOTCH1 coactivator complex bind promoters of Hey genes (4396387)