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Details on Person Activation and dimerization of c-JUN in the nucleus

Class:Id	Reaction:438026
_displayName	Activation and dimerization of c-JUN in the nucleus
_doRelease	TRUE
_timestamp	2010-12-02 14:36:28
authored	[InstanceEdit:438031] Shamovsky, V, 2009-09-22
catalystActivity	[CatalystActivity:438001] JUN kinase activity of phosphorylated JNK homologs [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:438021] Shamovsky, V, 2009-09-22
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[Reaction:168136] Activated JNKs phosphorylate c-JUN [Homo sapiens]
input	[EntityWithAccessionedSequence:438016] c-JUN [nucleoplasm] [Gallus gallus] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:438016] c-JUN [nucleoplasm] [Gallus gallus] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm]
literatureReference	[LiteratureReference:437979] c-Jun expression, activation and function in neural cell death, inflammation and repair
modified	[InstanceEdit:451539] Shamovsky, V, 2010-01-05 [InstanceEdit:571303] Shamovsky, V, 2010-04-09 [InstanceEdit:674710] Shamovsky, V, 2010-05-05 [InstanceEdit:680254] Shamovsky, V, 2010-05-05 [InstanceEdit:796980] Shamovsky, V, 2010-05-24 [InstanceEdit:844693] Shamovsky, V, 2010-05-28 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation and dimerization of c-JUN in the nucleus
output	[Complex:437991] activated c-JUN dimer [nucleoplasm] [Gallus gallus] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent	[Reaction:437995] Activated JNK migrates to the nucleoplasm [Gallus gallus] [Reaction:438005] MKK4 phosphorylates JNK [Gallus gallus]
regulatedBy	[NegativeRegulation:442857] Negative regulation by 'MAPK phosphatases [nucleoplasm]'
releaseDate	2010-12-14
reviewed	[InstanceEdit:789693] D'Eustachio, P, 2010-05-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1104895] R-GGA-438026.3
summation	[Summation:446230] Shortly after phosphorylation JNKs are translocated to nucl...
(hasEvent)	[Pathway:437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation [Gallus gallus]
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No pathways have been reviewed or authored by Activation and dimerization of c-JUN in the nucleus (438026)