Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes

Class:IdLiteratureReference:437996
_displayNameSimultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes
_timestamp2009-09-22 15:45:43
author[Person:438000] Thiefes, A
[Person:438011] Wolter, S
[Person:438003] Mushinski, JF
[Person:437958] Hoffmann, E
[Person:437964] Dittrich-Breiholz, O
[Person:437988] Graue, N
[Person:437974] Dörrie, A
[Person:437700] Schneider, H
[Person:437982] Wirth, D
[Person:438004] Luckow, B
[Person:437997] Resch, K
[Person:437961] Kracht, M
created[InstanceEdit:438021] Shamovsky, V, 2009-09-22
journalJ Biol Chem
pages27728-41
pubMedIdentifier15837794
titleSimultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes
volume280
year2005
(literatureReference)[Pathway:437980] Activated TAK1 mediates p38 MAP kinase phosphorylation [Gallus gallus]
[Reaction:437984] Phosphorylation of MKK3/MKK6 by activated TAK1 [Gallus gallus]
[Pathway:437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation [Gallus gallus]
[Reaction:437999] Phosphorylation of MKK4 by activated TAK1 [Gallus gallus]
[Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation [Homo sapiens]
[Pathway:450302] activated TAK1 mediates p38 MAPK activation [Homo sapiens]
[Pathway:450321] JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 [Homo sapiens]
[Reaction:450337] Activated TAK1 phosphorylates MKK4/MKK7 [Homo sapiens]
[Reaction:450346] activated human TAK1 phosphorylates MKK3/MKK6 [Homo sapiens]
[Pathway:451524] MAPK activation in TLR cascade [Gallus gallus]
[Change default viewing format]
No pathways have been reviewed or authored by Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes (437996)