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Details on Person Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes
| Class:Id | LiteratureReference:437996 |
| _displayName | Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes |
| _timestamp | 2009-09-22 15:45:43 |
| author | [Person:438000] Thiefes, A [Person:438011] Wolter, S [Person:438003] Mushinski, JF [Person:437958] Hoffmann, E [Person:437964] Dittrich-Breiholz, O [Person:437988] Graue, N [Person:437974] Dörrie, A [Person:437700] Schneider, H [Person:437982] Wirth, D [Person:438004] Luckow, B [Person:437997] Resch, K [Person:437961] Kracht, M |
| created | [InstanceEdit:438021] Shamovsky, V, 2009-09-22 |
| journal | J Biol Chem |
| pages | 27728-41 |
| pubMedIdentifier | 15837794 |
| title | Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes |
| volume | 280 |
| year | 2005 |
| (literatureReference) | [Pathway:437980] Activated TAK1 mediates p38 MAP kinase phosphorylation [Gallus gallus] [Reaction:437984] Phosphorylation of MKK3/MKK6 by activated TAK1 [Gallus gallus] [Pathway:437986] Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation [Gallus gallus] [Reaction:437999] Phosphorylation of MKK4 by activated TAK1 [Gallus gallus] [Pathway:445989] TAK1-dependent IKK and NF-kappa-B activation [Homo sapiens] [Pathway:450302] activated TAK1 mediates p38 MAPK activation [Homo sapiens] [Pathway:450321] JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 [Homo sapiens] [Reaction:450337] Activated TAK1 phosphorylates MKK4/MKK7 [Homo sapiens] [Reaction:450346] activated human TAK1 phosphorylates MKK3/MKK6 [Homo sapiens] [Pathway:451524] MAPK activation in TLR cascade [Gallus gallus] |
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No pathways have been reviewed or authored by Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes (437996)