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Details on Person Glycoprotein VI (GPVI) was identified as a collagen receptor...
| Class:Id | Summation:437383 |
|---|---|
| _displayName | Glycoprotein VI (GPVI) was identified as a collagen receptor... |
| _timestamp | 2023-10-10 06:55:14 |
| created | [InstanceEdit:437385] Jupe, S, 2009-09-17 |
| literatureReference | [LiteratureReference:445648] Platelet glycoprotein VI [LiteratureReference:437384] Platelet glycoprotein VI: its structure and function |
| modified | [InstanceEdit:437386] Jupe, S, 2009-09-17 [InstanceEdit:445654] Jupe, S, 2009-11-02 [InstanceEdit:9846295] Shamovsky, Veronica, 2023-10-10 |
| text | Glycoprotein VI (GPVI) was identified as a collagen receptor from studies of patients with a GPVI deficiency. GPVI-deficient platelets lack collagen-induced aggregation and the ability to form thrombi on a collagen surface under flow conditions. GPVI complexes with the Fc epsilon R1 receptor gamma chain, with a possible stoichiometry of two GPVI molecules and one FceRI gamma-chain dimer (Jung & Moroi 2008). GPVI binding to FcR gamma is necessary for high affinity GPVI binding to collagen. |
| (summation) | [Reaction:210282] Interaction of GPVI and FceRI gamma [Homo sapiens] |
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No pathways have been reviewed or authored by Glycoprotein VI (GPVI) was identified as a collagen receptor... (437383)
