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Details on Person 3-phosphoinositide dependent protein kinase-1 (Pdpk1, also k...
| Class:Id | Summation:437262 |
|---|---|
| _displayName | 3-phosphoinositide dependent protein kinase-1 (Pdpk1, also k... |
| _timestamp | 2019-01-11 22:19:06 |
| created | [InstanceEdit:437270] Jupe, S, 2009-09-14 |
| literatureReference | [LiteratureReference:437190] Regulation of protein kinase C zeta by PI 3-kinase and PDK-1 |
| modified | [InstanceEdit:437308] Jupe, S, 2009-09-14 [InstanceEdit:9634616] Rothfels, Karen, 2019-01-11 |
| text | 3-phosphoinositide dependent protein kinase-1 (Pdpk1, also known as Pdk1 and PKB kinase because of its activity at Protein kinase B) phosphorylates T410 of protein kinase C zeta type (Prkcz, also known as PKC zeta), leading to activation. The motif surrounding T410 is highly conserved in other PKC family members suggesting that Pdpk1 might activate other PKCs. |
| (summation) | [Reaction:437185] PDK1 activates PKC zeta [Rattus norvegicus] [Reaction:437195] PDPK1 activates PRKCZ [Homo sapiens] |
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No pathways have been reviewed or authored by 3-phosphoinositide dependent protein kinase-1 (Pdpk1, also k... (437262)
