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Details on Person Sin3-type complex

Class:Id	GO_CellularComponent:436638
_displayName	Sin3-type complex
_timestamp	2014-02-11 02:12:15
accession	0070822
componentOf	[GO_CellularComponent:22621] nuclear chromosome [GO_CellularComponent:171405] nuclear lumen [GO_CellularComponent:352] nucleus [GO_CellularComponent:78322] chromatin [Compartment:1598585] chromosome [GO_CellularComponent:354] intracellular anatomical structure
created	[InstanceEdit:436347] Kanapin, EE
definition	Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.
instanceOf	[GO_CellularComponent:21597] histone deacetylase complex [GO_CellularComponent:9715812] nuclear protein-containing complex [GO_CellularComponent:258170] protein-containing complex [GO_CellularComponent:357] cellular_component [GO_CellularComponent:5263325] catalytic complex [GO_CellularComponent:258170] protein-containing complex [GO_CellularComponent:357] cellular_component
modified	[InstanceEdit:447572] Kanapin, EE [InstanceEdit:526073] Kanapin, AA [InstanceEdit:528085] Kanapin, AA [InstanceEdit:615500] Kanapin, AA [InstanceEdit:797782] Kanapin, AA [InstanceEdit:937668] Yung, CK [InstanceEdit:1042299] Yung, CK [InstanceEdit:1220942] Yung, CK [InstanceEdit:1301023] Yung, CK [InstanceEdit:1552540] Yung, CK [InstanceEdit:1996004] Yung, CK [InstanceEdit:2132408] Weiser, JD [InstanceEdit:2133145] Weiser, JD [InstanceEdit:2266147] Weiser, JD [InstanceEdit:2454362] Weiser, JD [InstanceEdit:2455542] Weiser, JD [InstanceEdit:2587907] Weiser, JD [InstanceEdit:3132285] Weiser, JD [InstanceEdit:3445953] Weiser, JD [InstanceEdit:4341211] Weiser, JD [InstanceEdit:5083267] Weiser, JD [InstanceEdit:5263134] Weiser, JD [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689214] Cook, Justin, 2020-05-15 [InstanceEdit:9715775] Shorser, Solomon, 2021-02-17 [InstanceEdit:9715950] Shorser, Solomon, 2021-02-17 [InstanceEdit:9730069] Shorser, Solomon, 2021-05-05 [InstanceEdit:9750511] Weiser, JD, 2021-08-11 [InstanceEdit:9758049] Weiser, JD, 2021-11-08 [InstanceEdit:9767446] Wright, Adam, 2022-02-25 [InstanceEdit:9773560] Weiser, Joel, 2022-05-04 [InstanceEdit:9910546] Weiser, Joel, 2024-05-14 [InstanceEdit:9917761] Weiser, Joel, 2024-08-09 [InstanceEdit:9926777] Weiser, Joel, 2024-11-03 [InstanceEdit:9939260] Weiser, Joel, 2025-02-21 [InstanceEdit:9948590] Weiser, Joel, 2025-05-21 [InstanceEdit:9963890] Weiser, Joel, 2025-08-15 [InstanceEdit:9970828] Weiser, Joel, 2025-10-31 [InstanceEdit:9983368] Weiser, Joel, 2026-02-22 [InstanceEdit:9989188] Weiser, Joel, 2026-05-15
name	Sin3-type complex
referenceDatabase	[ReferenceDatabase:1] GO
(goCellularComponent)	[Complex:992748] p53:MYB:SIN3A [nucleoplasm] [Homo sapiens]
(instanceOf)	[GO_CellularComponent:262672] Rpd3S complex [GO_CellularComponent:263855] Rpd3L complex
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No pathways have been reviewed or authored by Sin3-type complex (436638)