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Query author contributions in Reactome

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Details on Person UniProt:Q8TAP6-3 CEP76

Class:IdReferenceIsoform:435879
_chainChangeLogchain:1-659 added on Sat February 7 2015
_displayNameUniProt:Q8TAP6-3 CEP76
_timestamp2024-11-03 19:40:20
chainchain:1-659
checksum66EB85DCDCBEE518
commentFUNCTION Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.SUBUNIT Interacts with CCP110 and CEP97.INTERACTION Does not localize along the ciliary axoneme.ALTERNATIVE PRODUCTS Expressed at low level in G1 and is induced in S and G2 phase, during which point centrioles have already commenced duplication (at protein level).SIMILARITY Belongs to the CEP76 family.SEQUENCE CAUTION Truncated C-terminus.
created[InstanceEdit:435871] Kanapin, AA
descriptionrecommendedName: Centrosomal protein of 76 kDa shortName: Cep76
geneNameCEP76
C18orf9
identifierQ8TAP6
isoformParent
isSequenceChangedFALSE
keywordAlternative splicing
Cytoplasm
Cytoskeleton
Phosphoprotein
Proteomics identification
Reference proteome
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameCEP76
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8989434] ENSEMBL:ENSG00000101624 CEP76 [Homo sapiens]
secondaryIdentifierCEP76_HUMAN
B0YJB2
B4DXG5
B4DZW1
Q658N5
Q9H9U7
sequenceLength659
species[Species:48887] Homo sapiens
variantIdentifierQ8TAP6-3
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No pathways have been reviewed or authored by UniProt:Q8TAP6-3 CEP76 (435879)