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Details on Person UniProt:A2VDW6 NECAB3
| Class:Id | ReferenceGeneProduct:435483 |
|---|---|
| _chainChangeLog | chain:1-358 added on Fri February 6 2015 |
| _displayName | UniProt:A2VDW6 NECAB3 |
| _timestamp | 2023-11-03 16:05:43 |
| chain | chain:1-358 |
| checksum | 697F002284A3B65B |
| comment | FUNCTION Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity). May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity).SUBUNIT Interacts with the N-terminal domain of APBA2. Interacts with NEK2 (By similarity). Interacts with APBA3; APBA3 seems to mediate the interaction between NECAB3 and HIF1AN (By similarity).SUBCELLULAR LOCATION Phosphorylated by NEK2. |
| created | [InstanceEdit:435478] Kanapin, AA |
| description | recommendedName: N-terminal EF-hand calcium-binding protein 3 alternativeName: Amyloid-beta A4 protein-binding family A member 2-binding protein alternativeName: X11L-binding protein 51 |
| geneName | NECAB3 APBA2BP XB51 |
| identifier | A2VDW6 |
| isSequenceChanged | FALSE |
| keyword | Calcium Golgi apparatus Metal-binding Phosphoprotein Reference proteome |
| modified | [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:3132113] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9027688] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | NECAB3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | NECA3_BOVIN |
| sequenceLength | 358 |
| species | [Species:48898] Bos taurus |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:A2VDW6 NECAB3 (435483)
