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Details on Person UniProt:Q9TZD0 lst-2
| Class:Id | ReferenceGeneProduct:435482 |
|---|---|
| _chainChangeLog | chain:1-661 added on Fri February 6 2015 |
| _displayName | UniProt:Q9TZD0 lst-2 |
| _timestamp | 2023-11-03 16:04:45 |
| chain | chain:1-661 |
| checksum | 9B2CFF7FD13B0E23 |
| comment | FUNCTION Negative regulator of epidermal growth factor receptor (EGFR) signaling.TISSUE SPECIFICITY Expressed in vulval precursor cells (VPCs).DEVELOPMENTAL STAGE Highly expressed in all 6 vulval precursor cells (VPCs). At the time of inductive signaling, expression forms a gradient in response to inductive signal: expression is low in P6.p, intermediate in P5.p and P7.p and undiminished in P3.p, P4.p, and P8.p. Later, expression becomes strong again in P5.p and P7.p.DISRUPTION PHENOTYPE Causes ectopic vulval induction.SIMILARITY Belongs to the lst-2 family. |
| created | [InstanceEdit:435478] Kanapin, AA |
| description | recommendedName: Lateral signaling target protein 2 |
| geneName | lst-2 R160.7 |
| identifier | Q9TZD0 |
| isSequenceChanged | FALSE |
| keyword | Metal-binding Reference proteome Zinc Zinc-finger |
| modified | [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | lst-2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | LST2_CAEEL |
| sequenceLength | 661 |
| species | [Species:68320] Caenorhabditis elegans |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9TZD0 lst-2 (435482)
