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Details on Person UniProt:A6ZPT1 AIM22
| Class:Id | ReferenceGeneProduct:435481 |
|---|---|
| _chainChangeLog | chain:1-409 added on Fri February 6 2015 |
| _displayName | UniProt:A6ZPT1 AIM22 |
| _timestamp | 2025-02-21 20:11:09 |
| chain | chain:1-409 |
| checksum | 1142B2F45343B9BF |
| comment | FUNCTION Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.CATALYTIC ACTIVITY L-lysyl-[lipoyl-carrier protein] + (R)-lipoate + ATP = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)PATHWAY Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.PATHWAY Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.SUBUNIT Monomer.MISCELLANEOUS In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.SIMILARITY Belongs to the LplA family. |
| created | [InstanceEdit:435478] Kanapin, AA |
| description | recommendedName: Putative lipoate-protein ligase A ecNumber: 6.3.1.20 alternativeName: Altered inheritance rate of mitochondria protein 22 |
| geneName | AIM22 SCY_2892 |
| identifier | A6ZPT1 |
| isSequenceChanged | FALSE |
| keyword | ATP-binding Ligase Nucleotide-binding |
| modified | [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | AIM22 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | LPLA_YEAS7 |
| sequenceLength | 409 |
| species | [Species:68322] Saccharomyces cerevisiae |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:A6ZPT1 AIM22 (435481)
