Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ZnT2 facilitates zinc vesicular sequestration

Class:Id	Reaction:435375
_displayName	ZnT2 facilitates zinc vesicular sequestration
_doRelease	TRUE
_timestamp	2025-08-13 17:46:29
authored	[InstanceEdit:435367] Jassal, Bijay, 2009-09-09
catalystActivity	[CatalystActivity:435356] zinc ion transmembrane transporter activity of SLC30A2 [endosome membrane]
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:435367] Jassal, Bijay, 2009-09-09
crossReference	[DatabaseIdentifier:9958080] RHEA:72629
edited	[InstanceEdit:433105] Jassal, Bijay, 2009-08-21
inferredFrom	[Reaction:437094] Znt2 facilitates zinc vesicular sequestration [Rattus norvegicus]
input	[SimpleEntity:29426] Zn2+ [cytosol] [SimpleEntity:74722] H+ [endosome lumen] [SimpleEntity:74722] H+ [endosome lumen]
literatureReference	[LiteratureReference:435352] ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration [LiteratureReference:9958072] ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion
modified	[InstanceEdit:437095] Jassal, Bijay, 2009-09-11 [InstanceEdit:446288] Jassal, Bijay, 2009-11-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9958073] Stephan, Ralf, 2025-06-19 [InstanceEdit:9958078] Stephan, Ralf, 2025-06-19 [InstanceEdit:9963146] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963151] Stephan, Ralf, 2025-08-13
name	ZnT2 facilitates zinc vesicular sequestration
output	[SimpleEntity:435350] Zn2+ [endosome lumen] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:442422] SLC39A1-4 transports Zn2+ from extracellular region to cytosol [Homo sapiens] [Reaction:442317] ZIP6 and ZIP14 mediate zinc influx into cells [Homo sapiens] [Reaction:442393] ZIP7 mediates zinc efflux from the endoplasmic reticulum [Homo sapiens] [Reaction:442387] ZIP8 mediates zinc influx into cells [Homo sapiens] [Reaction:442345] hZIP10 mediates zinc influx into cells [Homo sapiens] [Reaction:442405] hZIP5 mediates zinc uptake by cells [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2009-12-15
reviewed	[InstanceEdit:446289] He, Lei, 2009-11-12 [InstanceEdit:9962967] D'Eustachio, Peter, 2025-08-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104356] R-HSA-435375.3
structureModified	[InstanceEdit:9958073] Stephan, Ralf, 2025-06-19
summation	[Summation:435355] The human gene SLC30A2 encodes zinc transporter ZnT2. Its fu...
(hasEvent)	[Pathway:435368] Zinc efflux and compartmentalization by the SLC30 family [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9964621] Update Tracker - [Reaction:435375] ZnT2 facilitates zinc vesicular sequestration - v94:[modifyText, removeInput, removeLiteratureReference, removeOutput]
[Change default viewing format]

No pathways have been reviewed or authored by ZnT2 facilitates zinc vesicular sequestration (435375)