Query author contributions in Reactome
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Details on Person Zinc is an essential element for all organisms because it se...
| Class:Id | Summation:435346 |
|---|---|
| _displayName | Zinc is an essential element for all organisms because it se... |
| _timestamp | 2014-05-28 04:52:49 |
| created | [InstanceEdit:435367] Jassal, Bijay, 2009-09-09 |
| modified | [InstanceEdit:437088] Jassal, Bijay, 2009-09-11 [InstanceEdit:442374] Jassal, Bijay, 2009-09-25 [InstanceEdit:5577005] Matthews, Lisa, 2014-05-28 |
| text | Zinc is an essential element for all organisms because it serves as a catalytic or structural cofactor for many different proteins. Cellular zinc homoeostasis is co-ordinated through Zn2+-specific transporters which are members of two distinct gene families. Members of the SLC39 gene family (ZRTL-like import proteins1-14, ZIP1-14) are responsible for Zn2+ import into the cytoplasm, either across the plasma membrane or out of intracellular organelles. In contrast, members of the SLC30 gene family (zinc transporters 1-10, ZnT1-10) export Zn2+ from the cytoplasm, either across the plasma membrane into the extracellular space or into intracellular organelles (Murakami M and Hirano T, 2008; Devirgiliis C et al, 2007; Eide DJ, 2006). |
| (summation) | [Pathway:435354] Zinc transporters [Homo sapiens] |
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No pathways have been reviewed or authored by Zinc is an essential element for all organisms because it se... (435346)
