Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person LDL causes a transient increase in p38 MAPK activity in plat...
| Class:Id | Summation:435243 |
|---|---|
| _displayName | LDL causes a transient increase in p38 MAPK activity in plat... |
| _timestamp | 2017-05-12 16:22:45 |
| created | [InstanceEdit:435242] Jupe, S, 2009-09-08 |
| literatureReference | [LiteratureReference:432091] Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits low density lipoprotein-induced signaling in platelets [LiteratureReference:9006082] Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology |
| modified | [InstanceEdit:9006081] Jupe, Steve, 2017-05-12 |
| text | LDL causes a transient increase in p38 MAPK activity in platelets. After an initial phase in which LDL leads to the activation of p38MAPK, LDL leads to tyrosine phosphorylation and thereby activation of PECAM-1, which in turn leads to binding and stimulation of the Ser/Thr phosphatases PP1/PP2A which reduce the activity of p38MAPK by dephosphorylation. |
| (summation) | [BlackBoxEvent:435244] PECAM1 is phosphorylated [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by LDL causes a transient increase in p38 MAPK activity in plat... (435243)
