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Details on Person Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity
| Class:Id | LiteratureReference:434145 |
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| _displayName | Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity |
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| _timestamp | 2009-08-26 20:33:26 |
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| author | [Person:434096] Tenoever, BR
[Person:433949] Ng, SL
[Person:433885] Chua, MA
[Person:166858] McWhirter, SM
[Person:169068] Garcia-Sastre, A
[Person:72147] Maniatis, T |
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| created | [InstanceEdit:434122] Shamovsky, V, 2009-08-26 |
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| journal | Science |
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| pages | 1274-8 |
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| pubMedIdentifier | 17332413 |
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| title | Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity |
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| volume | 315 |
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| year | 2007 |
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| (literatureReference) | [Pathway:168936] Viral dsRNA:TLR3:TRIF Complex Activates TBK1/IKK epsilon [Homo sapiens]
[Pathway:433819] Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK [Gallus gallus]
[Reaction:433955] Phosphorylation of IKKs complex by activated TAK1 [Gallus gallus]
[Pathway:936964] Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) [Homo sapiens]
[Reaction:1227783] Phosphorylation of IKKs complex mediated by MEKK1 [Gallus gallus]
[Reaction:1227867] TANK binds polyubiquitinated TRAF3/6 [Gallus gallus]
[Reaction:1227885] TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation [Gallus gallus]
[Pathway:9013973] TICAM1-dependent activation of IRF3/IRF7 [Homo sapiens]
[Summation:433859] Embryonic fibroblast cells from TBK1-deficient mice show dec...
[Summation:433894] The IKKs - IkB kinase (IKK) complex serves as the master re... |
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