Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6

Class:Id	BlackBoxEvent:433981
_displayName	Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6
_doRelease	TRUE
_timestamp	2017-09-25 21:20:42
authored	[InstanceEdit:434153] Shamovsky, V, 2009-08-26
catalystActivity	[CatalystActivity:434017] ubiquitin-protein transferase activity of viral ds RNA : TLR3 : TICAM1 : TRAF6 [endosome membrane]
compartment	[Compartment:74700] endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:434122] Shamovsky, V, 2009-08-26
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[BlackBoxEvent:450259] Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex [Homo sapiens]
input	[Complex:446245] Ubiquitin:UBE2N : UBE2V complex [cytosol] [Gallus gallus] [Complex:433968] viral ds RNA : TLR3 : TICAM1 : TRAF6 [endosome membrane] [Gallus gallus]
literatureReference	[LiteratureReference:202511] Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
modified	[InstanceEdit:434572] Shamovsky, V, 2009-08-31 [InstanceEdit:446250] Shamovsky, V, 2009-11-11 [InstanceEdit:450360] Shamovsky, V, 2009-12-16 [InstanceEdit:451966] Shamovsky, V, 2010-01-14 [InstanceEdit:532629] Shamovsky, V, 2010-03-01 [InstanceEdit:532637] Gillespie, ME, 2010-03-02 [InstanceEdit:532638] Gillespie, ME, 2010-03-02 [InstanceEdit:674709] Shamovsky, V, 2010-05-05 [InstanceEdit:790884] Shamovsky, V, 2010-05-24 [InstanceEdit:796980] Shamovsky, V, 2010-05-24 [InstanceEdit:844693] Shamovsky, V, 2010-05-28 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:2581437] Shamovsky, V, 2012-11-12 [InstanceEdit:5255454] D'Eustachio, Peter, 2014-02-06 [InstanceEdit:9014710] Shamovsky, Veronica, 2017-08-02 [InstanceEdit:9022894] Shamovsky, Veronica, 2017-09-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6
output	[Complex:433960] UBE2N : UBE2V complex [cytosol] [Gallus gallus] [Complex:434102] viral ds RNA : TLR3 : TICAM1 : pUb-TRAF6 [endosome membrane] [Gallus gallus]
precedingEvent	[Reaction:433808] viral dsRNA: TLR3: TICAM1 recruits TRAF6 [Gallus gallus] [Reaction:433815] viral dsRNA : TRL3 recruits TICAM1 [Gallus gallus]
relatedSpecies	[Species:9014381] Infectious bronchitis virus
releaseDate	2010-12-14
reviewed	[InstanceEdit:789693] D'Eustachio, P, 2010-05-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1105881] R-GGA-433981.4
summation	[Summation:202446] TRAF6 possesses ubiquitin ligase activity and undergoes K-63...
(hasEvent)	[Pathway:433871] TRAF6 mediated induction of proinflammatory cytokines [Gallus gallus]
(precedingEvent)	[BlackBoxEvent:433936] Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex dsRNA :TLR3 :TICAM1 [Gallus gallus]
(updatedInstance)	[_UpdateTracker:9788221] Update Tracker - [BlackBoxEvent:433981] Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 - v43:[modifyText] [_UpdateTracker:9789956] Update Tracker - [BlackBoxEvent:433981] Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 - v36:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 (433981)