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Details on Person Dimerized Phospho-IRF3 is Transported To The Nucleus

Class:Id	Reaction:433967
_displayName	Dimerized Phospho-IRF3 is Transported To The Nucleus
_doRelease	TRUE
_timestamp	2011-03-02 09:13:27
authored	[InstanceEdit:434153] Shamovsky, V, 2009-08-26
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:434122] Shamovsky, V, 2009-08-26
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
inferredFrom	[Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus [Homo sapiens]
input	[Complex:433903] Phosphorylated IRF3 : IRF3 dimer [cytosol] [Gallus gallus]
literatureReference	[LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
modified	[InstanceEdit:434573] Shamovsky, V, 2009-08-31 [InstanceEdit:451542] Shamovsky, V, 2010-01-05 [InstanceEdit:573301] Shamovsky, V, 2010-04-09 [InstanceEdit:674719] Shamovsky, V, 2010-05-05 [InstanceEdit:749437] Shamovsky, V, 2010-05-18 [InstanceEdit:796981] Shamovsky, V, 2010-05-24 [InstanceEdit:813673] Shamovsky, V, 2010-05-26 [InstanceEdit:844694] Shamovsky, V, 2010-05-28 [InstanceEdit:994004] Shamovsky, V, 2010-11-05 [InstanceEdit:1004540] D'Eustachio, P, 2010-11-09 [InstanceEdit:1008271] Shamovsky, V, 2010-11-10 [InstanceEdit:1216499] Shamovsky, V, 2011-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dimerized Phospho-IRF3 is Transported To The Nucleus
output	[Complex:434029] Phosphorylated IRF3 : IRF3 [nucleoplasm] [Gallus gallus]
precedingEvent	[Reaction:434027] Dimerization of Phospho-IRF3 [Gallus gallus] [Reaction:433826] Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3 [Gallus gallus] [Reaction:433786] Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 [Gallus gallus] [Reaction:1227881] Phosphorylation and release of IRF3 [Gallus gallus]
releaseDate	2010-12-14
reviewed	[InstanceEdit:789693] D'Eustachio, P, 2010-05-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:1104303] R-GGA-433967.2
summation	[Summation:813672] Phosphorylation and dimerization of IRF3 results in the cyto...
(hasEvent)	[Pathway:433819] Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK [Gallus gallus] [Pathway:434136] Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 [Gallus gallus] [Pathway:1227882] TRAF mediated activation of IRF [Gallus gallus]
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