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Details on Person sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP

Class:Id	Reaction:433606
_displayName	sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP
_doRelease	TRUE
_timestamp	2023-09-08 10:54:46
catalystActivity	[CatalystActivity:433565] sphingosine kinase activity of SPHK1 [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:433625] D'Eustachio, P, 2009-08-22
inferredFrom	[Reaction:428273] SPHK1 phosphorylates sphingoid [Homo sapiens]
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:428163] SPA [endoplasmic reticulum membrane]
modified	[InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1168648] D'Eustachio, P, 2011-01-03 [InstanceEdit:1667320] D'Eustachio, P, 2011-10-14 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9843384] Stephan, Ralf, 2023-09-08
name	sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:428275] SPAP [cytosol]
precedingEvent	[Reaction:433576] 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ [Gallus gallus] [Reaction:433550] palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 [Gallus gallus]
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016551] R-GGA-433606.4
summation	[Summation:433533] SPHK1 (sphingosine kinase 1) catalyzes the reaction of sphin...
(hasEvent)	[Pathway:433584] Sphingolipid metabolism [Gallus gallus]
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No pathways have been reviewed or authored by sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP (433606)